⁣When a colorful frontier woman is murdered, Dr. Baxter introducing the fingerprint technique, sets out to find the murderer.

⁣While sick Apaches are being treated for a fatal illness, one murders a U.S Cavalry colonel. .

⁣Fur theives are looting the traps on the ranch where Roy is foreman and they have murdered one of Roy's friends. To complicate matters, the ranch owner, unknown to Roy, arrives with her girlfriend posing as a member of the lonely hearts club. Roy gets a tip on the outlaws but it's a trap and Roy and the boys soon find themselves in jail with the townspeople and trappers on the way to Lynch them.

⁣After he loses his money and horse in a poker game, Yak learns he was cheated. But then he learns that the men that cheated him are wanted and have a price on their heads. This gives him a chance to get his money back and more, so he sets out after them.

⁣Bill falls for a pretty girl when she and her father arrive in Wileyville. He and Judge Wiley convince the newcomers to buy the stagecoach line. When the pretty blonde learns the railroad is building a spur to Wileyville, she blames Buffalo Bill for encouraging the bad business deal.

⁣When a bank president is murdered, the townspeople accuse the man's future son-in-law of the crime and a lynching party is formed. Cisco and Pancho must find out who the real killers are before the mob hangs the innocent man.

⁣Dr. Baxter is captured by a gang of outlaws who need him to patch up a wound. .